2,4-Piperadinedione CAS Number 50607-30-2

Basic Info

Model No.: 50607-30-2

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Certificate: ISO

Product Description

2,4-Piperadinedione cas number is 50607-30-2, Molecular formula C5H7NO2, Molecular weight 113.11, the appearance is light yellow to white powder. 2,4-piperadinedione is an important pharmaceutical intermediates, its derivatives are widely used in anti-bacterial, anti-tumor and other fields. Its traditional synthetic process is use monoethyl malonate as raw material,use thionyl chloride as solvent, heated to reflux to obtain acid chloride, and then react with 3-aminopropionic acid ethyl ester to synthesis of 2,4-piperadinedione, The raw material used in process has strong corrosive, and easy to produce by-products and make the product darker, will cause pollution to the environment in industrial production. So we adjusted the route. The current synthesis method with monomethyl malonate and methyl 3-aminopropionate hydrochloride as the starting material, after acylation, condensation and other reactions, and then under the action of sodium methacrylate,through ring-forming condensation reaction to get 3- (methyl (Methoxycarbonyl)) - 4-carbonyl-1,4,5,6-tetrahydropyridine-2-ol, and then decarboxylated in the hydrochloric acid system to 2,4-piperadinedione, Since the methoxy group is easily removed, the reaction condition is mild, the operation is safe and the conversion rate is high.
Thera. Category:Pharmaceutical Intermediates   

Cas No.:  50607-30-2

Synonym:PIPERIDIN-2,4-DIONE;Piperidine-2,4-dione;dihydropyridine-4,6-dione;2,4-Dioxopiperidine;2,4-Piperidinedione, 95+%;2,4-Diketopiperidine;2,4-PIPERADINEDIONE;2,4-Piperidinedione;

Molecular Formula:C5H7NO2

Molecular Weight:113.11

Assay: ≥99.%

Packing: Export worthy packing

lMaterial Safety Data Sheet: Available on request