Unit Price: | USD 1.0000 / Kilogram |
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Payment Type: | T/T |
Incoterm: | CIF |
Min. Order: | 1 Kilogram |
Delivery Time: | 15 Days |
Basic Info
Model No.: 24522-30-3
Additional Info
Packaging: AS REQUIRED
Productivity: KGS
Brand: VOLSENCHEM
Transportation: Air
Place of Origin: CHINA
Supply Ability: TRUE MANUFACTURER
Certificate: ISO
Product Description
The specific preparation process Teriflunomide intermediate of 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide cas 24522-30-3 was as follows: 205 g of sodium azide, 400 g of 4-trifluoromethylbenzoic acid, 52.4 g of triphenylphosphine, and 28 g of N-chlorosuccinimide were sequentially added to a 3 L round bottom flask. 2.4 L of tetrahydrofuran was stirred and reacted at 15℃ or 5 hours, and the reaction was followed until the reaction of the starting material was completed. After the completion of the reaction, 1.8 L of a solvent was removed under reduced pressure, and then the mixture was poured into 2 L of distilled water, stirred for 30 min, and filtered, and the filter cake was washed with 200 mL of distilled water and 200 mL of ethanol to obtain 388 g of a white solid compound 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide cas 24522-30-3 which is intermediate of Teriflunomide
2-Cyano-N-[4-(Trifluoromethyl)phenyl]acetamide CAS 24522-30-3 is the chemical name of Teriflunomide Intermediate. Teriflunomide is the active metabolite of leflunomide with antiinflammatory, antiproliferative, and immunosuppressive properties. Teriflunomide Intermediate CAS NO 24522-30-3 is pale yellow to white powder offered by our company with competitive price. Teriflunomide Intermediate 24522-30-3 has the purity by HPLC more than 99%, and loss on drying less than 0.3%, residue on ignition not more than 0.1%. The latest production batch of Teriflunomide Intermediate is in March,2016, which has 500 gram in stock.
Thera. Category: antiinflammatory
Cas No.: 24522-30-3
Synonym:2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide;AcetaMide, 2-cyano-N-[4-(trifluoroMethyl)phenyl]-;Leflunomide Impurity H;Leflunomide EP Impurity H
Molecular Formula: C10H7F3N2O
Molecular Weight:
Assay: ≥99.%
Packing: Export worthy packing
lMaterial Safety Data Sheet: Available on request
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