2-Cyano-N-[4-(Trifluoromethyl)Phenyl]Acetamide CAS 24522-30-3

Basic Info

Model No.: 24522-30-3

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Certificate: ISO

Product Description

The specific preparation process Teriflunomide intermediate of 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide cas 24522-30-3 was as follows: 205 g of sodium azide, 400 g of 4-trifluoromethylbenzoic acid, 52.4 g of triphenylphosphine, and 28 g of N-chlorosuccinimide were sequentially added to a 3 L round bottom flask. 2.4 L of tetrahydrofuran was stirred and reacted at 15℃ or 5 hours, and the reaction was followed until the reaction of the starting material was completed. After the completion of the reaction, 1.8 L of a solvent was removed under reduced pressure, and then the mixture was poured into 2 L of distilled water, stirred for 30 min, and filtered, and the filter cake was washed with 200 mL of distilled water and 200 mL of ethanol to obtain 388 g of a white solid compound 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide cas 24522-30-3 which is intermediate of Teriflunomide

2-Cyano-N-[4-(Trifluoromethyl)phenyl]acetamide CAS 24522-30-3 is the chemical name of Teriflunomide Intermediate. Teriflunomide is the active metabolite of leflunomide with antiinflammatory, antiproliferative, and immunosuppressive properties. Teriflunomide Intermediate CAS NO 24522-30-3 is pale yellow to white powder offered by our company with competitive price. Teriflunomide Intermediate 24522-30-3 has the purity by HPLC more than 99%, and loss on drying less than 0.3%, residue on ignition not more than 0.1%. The latest production batch of Teriflunomide Intermediate is in March,2016, which has 500 gram in stock. 

Thera. Category:  antiinflammatory

Cas No.: 24522-30-3

Synonym:2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide;AcetaMide, 2-cyano-N-[4-(trifluoroMethyl)phenyl]-;Leflunomide Impurity H;Leflunomide EP Impurity H

Molecular Formula: C10H7F3N2O

Molecular Weight:

Assay: ≥99.%

Packing: Export worthy packing

lMaterial Safety Data Sheet: Available on request