Anti-tuberculosis Drug Bedaquiline FuMarate CAS 845533-86-0

Basic Info

Model No.: 845533-86-0

Function: Nutritional Therapeutics

Grade Standard: Medicine Grade

State: Solid

Volatile: Not Volatile

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Certificate: ISO

Product Description

Bedaquiline FuMarate CAS Number 845533-86-0 is inhibiting the Mycobacterium tuberculosis ATP synthase proton pump activity, to affect the Mycobacterium tuberculosis ATP synthesis, which play an antibacterial and bactericidal effect. Clinically used for the treatment of adult multi-drug resistant tuberculosis. It has the same bactericidal activity on Mycobacterium tuberculosis-sensitive strains and resistant strains, and also has a good sterilization of the dormant bacteria. Compared with the existing anti-tuberculosis drugs, beidaquinoline has a new anti-tuberculosis mechanism, and has no cross-resistancethe with existing anti-TB drugs. Bedaquiline FuMarate has good oral absorption.   and also good bioavailability after food ,most of Bedaquiline FuMarate and metabolites excreted by feces, only 1% to 4% through urine discharge.

Thera. Category:Anti-tuberculosis 

Cas No.:  845533-86-0

Synonym:(1R,2S)-1-(6-broMo-2-Methoxyquinolin-3-yl)-4-(diMethylaMino)-2-naphthalen-1-yl-1-phenylbutan-2-ol,(E)-but-2-enedioic acid;Bedaquiline (fuMarate);R 403323;

Molecular Weight: 653.56162

Molecular formula: C36H33BrN2O5

Purity: ≥99.%

Packing:Export worthy packing

Material Safety Data Sheet:Available on request