CDK4/CDK6 Inhibitor​ LEE011; LEE 011;LEE-011|Ribociclib CAS 1211441-98-3

Basic Info

Model No.: 1211441-98-3

Grade Standard: Medicine Grade

State: Solid

Additional Info

Packaging: 1G,2G,10Gram

Productivity: Custom Manufacturing

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: In stock

Product Description

CDK4/CDK6 Inhibitor LEE011; LEE 011;LEE-011|Ribociclib CAS 1211441-98-3   Ribociclib as known as LEE -011 CAS number is 1211441-98-3, it is an orally active cyclin-dependent kinase CDK4 / 6 inhibitor,LEE011 entered the clinical phase III, its study is much earlier than its previous estimates. According to the two completed studies showed that the LEE011 anticancer effect is satisfactory, and we believe that the effect of LEE011 has similar with palbociclib.The study found that LEE011 combined with letrozole therapy in advanced breast cancer patients without progression-free survival (PFS) has significance clinical, The purity of Ribociclib is above 99.9%. All quotations are included domestic and international transport costs and invoice costs. The stock is changing at any time, for exact stock details, please contact our sales staff to confirm.

Thera Category: Anti-cancer

Cas No.: 1211441-98-3

Synonym:LEE 011 7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide;LEE011, >=98%;LEE-011, Ribociclib;7H-Pyrrolo[2,3-d]pyrimidine-6-carboxamide, 7-cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-; 7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide;7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide;7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide LEE 011;

Molecular Formula: C23H30N8O

Molecular Weight: 434.5373

Specifications: Available on request

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Related Ribociclib(LEE011) intermediate: 

 7H-Pyrrolo[2,3-d]pyrimidine-6-methanol, 2-chloro-7-cyclopentyl CAS 1374639-77-6

1-Piperazinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester CAS 571188-59-5