Lubiprostone (RU-0211) Treat For Chronic Idiopathic Constipation CAS 333963-40-9

Basic Info

Model No.: 333963-40-9

Additional Info

Packaging: As required

Productivity: Commercial

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Certificate: Technical Support

Product Description

Lubiprostone (RU-0211) CAS number is 333963-40-9, his appearance is white, odorless crystalline or crystalline powder, very soluble in ether and ethanol, soluble in medium chain triglycerides, almost insoluble with hexane and water. Lubiprostone cas 333963-40-9 is a localized chloride channel activator that selectively activates type 2 chloride channel (CIC-2) located on the cell membrane of the gastrointestinal tract of the gastrointestinal tract, increasing intestinal secretion and intestinal movement, thereby increasing bowel movements, alleviating the symptoms of chronic idiopathic constipation without changing the concentration of sodium and potassium in the plasma. For the treatment of adult chronic idiopathic constipation, constipation-type irritable bowel syndrome (only for female patients over 18 years old). In 2006, the FDA approved lubiprostone for chronic idiopathic constipation. In 2008, the new indication constipation-type irritable bowel syndrome was approved. The FDA approved the drug for the treatment of constipation caused by opioids. Three randomized double-blind controlled trials evaluated the safety and efficacy of lubiprostone. In a critical clinical trial, 431 patients were divided into 24 μg lubiprosone-treated and placebo groups. The overall response rate was 27.1%, compared with 18.9% in the placebo group.

Thera. Category:Constipation Treatment

Cas No.:333963-40-9

Synonyms:AMitiza Lubiprostone; (2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-heptanoic acid;Lubiprostone;Prostan-1-oic acid, 11,15-epoxy-16,16-difluoro-15-hydroxy-9-oxo-,( 56985540,11alpha,15R)-;Spi 0211;Unii-7662kg2R6k;(2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-h;7-((1R,2R,3R)-2-(4,4-difluoro-3-oxooctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid;

NW: 390.46

M.W.:C20H32F2O5

Assay: ≥99%

Packing:Export worthy packing

Material Safety Data Sheet:Available on request