Posaconazole Intermediates 1-(4-Aminophenyl)-4-(4-Hydroxyphenyl)Piperazine CAS 74853-08-0

Payment Type: L/C,T/T,D/P,D/A
Min. Order: 1 Gram

Basic Info

Model No.: 74853-08-0

Additional Info

Productivity: Customized

Brand: VOLSENCHEM

Transportation: Ocean,Air

Place of Origin: CHINA

Supply Ability: COMMERCIAL

Product Description

The synthesis route of 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine cas number 74853-08-0 can be found in the literature, but it has shortcomings which not good to large scale production,such as too long routes, harsh reaction conditions, extensive use of expensive catalysts, Serious environmental pollution. After a long period of optimization and analysis, our synthesis process is gradually mature. We used p-methoxy aniline and N, N-bis (2-haloethyl) -4-nitroaniline as raw materials, in aprotic solvents, alkaline conditions, process the condensation cyclization, and finally catalytic hydrogenation to obtain 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine 74853-08-0. It should be noted that during the reaction, the temperature and the use of the catalyst have a significant effect on the yield.

  • Thera. Category: Anti-fungal
  • Cas No.: 74853-08-0
  • Synonym4-(4-(4-AMINOPHENYL)-1-PIPERZINYL)PHENOL;1-(4-AMINOPHENYL)-4-(4-HYDROXYPHENYL)PIPERAZINE;4-HYDROXYPHENYLAMINOPHENYLPIPERAZINE;4-[4-(4-aMinophenyl)piperazin-1-yl]phenol;Phenol, 4-[4-(4-aMinophenyl)-1-piperazinyl]-;POSACONZOLE INTERMEDIATE;4-[4-(4-aMinophenyl)piperazino]phenol
  • Molecular Formula: C16H19N3O
  • 74853-08-0
  • Molecular Weight: 269.34
  • Pharmacopeia: in house spe.
  • Specifications:Available on request
  • Packing:Export worthy packing
  • Material Safety Data Sheet:Available on request

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3) 183871-36-5, [(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazine

4) 1-(4-Aminophenyl)-4-(4-Hydroxyphenyl)Piperazine CAS 74853-08-0

5) 2-[(1S,2S)-1-Ethyl-2-(Phenylmethoxy)propyl]hydrazinecarboxaldehyde  CAS 170985-85-0

6) 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,

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