AP26113;AP-26113 (Brigatinib) CAS 1197953-54-0

Unit Price: USD 1.0000 / Kilogram
Payment Type: T/T
Incoterm: CIF
Min. Order: 1 Kilogram
Delivery Time: 15 Days

Basic Info

Model No.: 1197953-54-0

Additional Info

Packaging: AS REQUIRED

Productivity: KGS


Transportation: Air

Place of Origin: CHINA


Product Description

Brigatinib CAS number 1197953-54-0 referred to as AP26113, it is an inhibitor of lung cancer ALK target, is a non-small cell lung cancer targeted drugs. AP26113 is generally used after   Crizotinib resistance, so in 2014 year the FDA awarded its tyrosine kinase inhibitor drug AP26113 orphan drug qualification for the treatment of methotrexate-resistant anaplastic lymphoma kinase Positive (ALK +) metastatic non-small cell lung cancer (NSCLC) patients. It has been shown that AP26113 inhibits at least 10 times more potency and selectivity than ALK bikazolidine , and that AP26113 is also effective for brain metastases in lung cancer.
Lung cancer ALK target is actually a small market, because the probability of lung cancer ALK mutation is not high, but crizotinib in this area is ALK inhibitor currently the only one listed , the effect is also very good, AP26113 CAS number 1197953-54-0 is the second Models, can be considered the second generation of ALK inhibitors, AP26113 is expected to break the monopoly position of crizotinib.
Thera. Category: Anti-cancer

Cas No.:1197953-54-0

Synonyms:5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4-pyrimidinediamine;Brigatinib;AP26113 (Brigatinib);Brigatinib, AP26113;


Molecular Formula:C29H39ClN7O2P

Molecular Weight: 584.10176 

Purity: ≥98%

Packing: Export worthy packing

Material Safety Data Sheet: Available on request 









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