Cabozantinib or CABXL-184 CAS 849217-68-1

Basic Info

Model No.: 849217-68-1

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Product Description

Cabozantinib as known as CABXL-184 CAS number 849217-68-1 which Is a novel multi-target tyrosine kinase inhibitor, as a regulator of MET, vascular endothelial growth factor receptor 2 (VEGFR2) and RET tyrosine Kinase inhibitors that can block the development and progression of tumor cells and are clinically used in the treatment of patients with progressive, metastatic thyroid medullary carcinoma (MTC). In vitro biochemical and cytological analysis showed that Cabozantinib can inhibit a variety of kinase activity and play an anti-tumor effect, kill tumor cells, reduce metastasis and inhibit tumor angiogenesis. patients treated with Cabozantinib,the incidence of gastrointestinal perforation and fistula formation was 3% and 1% respectively, For patients with perforation or fistula formation, Cabozantinib CAS 849217-68-1 should be terminated immediately. A large number of clinical experimental data show that the efficacy of Cabozantinib is significantly better than everolimus.

Thera. Category: anti cancer

Cas No.: 849217-68-1

Synonym: XL-184 free base (Cabozantinib);BMS907351;N-(4-((6,7-DiMethoxyquino;N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;Cabozantinib;N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide;XL184;Cabozantinib(XL184);

Molecular Formula:C28H24FN3O5

Molecular Weight: 502                  

Assay: ≥99.%

Packing: Export worthy packing

lMaterial Safety Data Sheet: Available on request

Usage: Synthesis Pharmaceutical Intermediates