CAS 1032903-50-6,Ceritinib Intermediate

Unit Price: USD 1000.0000 - 2000.0000 / Kilogram
Payment Type: T/T
Incoterm: FOB
Min. Order: 1 Kilogram
Delivery Time: 15 Days

Basic Info

Model No.: 1032903-50-6

Additional Info

Packaging: AS REQUIRED

Productivity: KGS


Place of Origin: CHINA


Certificate: ISO

Product Description

The Ceritinib intermediate cas number 1032903-50-6 synthesis of experimental steps are as follows: use 2-chloro-4-fluorotoluene as raw materials, through one step reaction to get the first step intermediate of 2-chloro-4-fluoro-5-nitrotoluene. As we had been detained description of  2-chloro-4-fluoro-5-nitrotoluene, so we do not repeat here. We will detail introduce the second step of the reaction process,dissolved the first step intermediate2-chloro-4-fluoro-5-nitrotoluen in 1200ml isopropanol and then added to 2L three bottles. Add 429 g of anhydrous potassium carbonate powder and stir to raise temperature to reflux. The reaction was allowed to proceed under reflux for 30 hours. Concentrate to remove most of the isopropanol. Add 2L of water, extracted twice with ethyl acetate, combined with ethyl acetate, washed with water. Ethyl acetate was concentrated to give the final brown product 1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene cas number 1032903-50-6.

l Thera. Category:Anti- cancer

l Cas No.: 1032903-50-6

l Synonym:(S)-N-tert-Butoxycarbonyl-3-hydroxypiperidine

l Molecular Formula:C10H12ClNO3

1032903-50-6 Ceritinib Intermediate

l Molecular Weight:229.66

l Assay: ≥98.%

l Packing:Export worthy packing

l Material Safety Data Sheet:Available on request

l Usage: Intermediate of Cerutinib

Related Intermediates : 

CAS 1032903-50-6,1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene 

CAS 76697-50-2,1-Amino-2-(isopropylsulphonyl)benzene

CAS 761440-16-8, 2,5-Dichloro-N-(2-(isopropylsulfonyl)-phenyl)pyrimidin-4-amine

2-chloro-4-fluoro-5-nitrotoluene CAS number 112108-73-3

[2-(isopropylthio)phenyl]amine hydrochloride CAS number  861343-73-9

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