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Dabigatran Eexilate Named BIBR-1048 CAS number 211915-06-9

Payment Type:	L/C,T/T
Incoterm:	FOB
Min. Order:	1 Kilogram
Delivery Time:	15 Days

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Basic Info

Model No.: 211915-06-9

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Certificate: ISO

Product Description

Dabigatran etexilate CAS number is 211915-06-9, a non-peptide thrombin inhibitor, is a prodrug of dabigatran that, after oral administration, is absorbed in the gastrointestinal tract and converted dabigatran which have direct anticoagulant activity in vivo. Thrombin plays an important role in the coagulation process. It is an extracellular insulin-like serine protease which, on the one hand, cleaves fibrinogen to fibrin, which participates in the formation of an insoluble thrombus matrix; on the other hand, it induces platelet activation And aggregation, which in turn lead to a series of secondary coagulation cascade reaction. Dabigatran exerts anticoagulant effects by direct inhibition of thrombin. It blocked the final steps of the clotting cascade network and thrombosis by binding to the fibrin-specific binding site of thrombin to prevent the cleavage of fibrinogen to fibrin. Dabigatran etexilate cas 211915-06-9 is the first new class of oral anticoagulant marketed after Warfarin over the past 50 years. It is orally available, potent, requires no special tests and has less drug interactions to reduce non-valvular atria Stroke risk in patients with tremor.
In October 2015, the US FDA approved dabigatran etexilate as a specific reversal agent. The availability of this drug offers a unique option for patients receiving dabigatran etexilate to reverse anticoagulation. which will further expand the scope and market size of dabigatran.

Thera. Category: Antithrombotic/Blood thinners

Cas No.: 211915-06-9

Synonym: Dabigatran Etexilate (free base);BIBR-1048(Dabigatran etexilate);N-[2-[4-[N-(Hexyloxycarbonyl)aMidino]phenylaMinoMethyl]-1-Methyl-1H-benziMidazol-5-ylcarbonyl]-N-(2-;BIBR 1048;BIBR-1048;Prazaxa;N-[[2-[[[4-[[[(Hexyloxy)carbonyl]aMidino]iMinoMethyl]phenyl]aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridyl-beta-alanine,ethyl ester;Pradaxa (dabigatran);

211915-06-9

Molecular Weight: 627.74

Molecular formula: C34H41N7O5

Assay: ≥98.%

Appearance: White Crystalline solid

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Usage: It can treat and prevent blood clots, reducing the risk of stroke.

Related intermediate:

CAS	Chemical Name	Specification		Color
41263-74-5	4-(MethylaMino)-3-nitrobenzoic acid	HPLC	≥99.0%	pale brown
103041-38-9	N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER	HPLC	≥99.0%	off white to white
429659-01-8	ETHYL N-[4-(METHYLAMINO)-3-NITROBENZOYL]-N-PYRIDIN-2-YL-SS-ALANINATE	HPLC	≥99.0%	orange yellow solid
42288-26-6	N-(4-CYANO-PHENYL)-GLYCINE	HPLC	≥99.0%	off white
42288-26-6	N-(4-CYANO-PHENYL)-GLYCINE	Loss on drying	≤1.0%	off white
212322-56-0	3-[(3-AMINO-4-METHYLAMINO-BENZOYL)-PYRIDIN-2-YL-AMINO]-PROPIONIC ACID ETHYL ESTER	HPLC	≥99.0%	off white
		Melting point	101.0°C~106.0°C
		Single impurity	≤0.3%
		Loss on drying	≤0.5%
		Residue on ignition	≤0.5%
		Assay	≥98.0%
211915-84-3	Synonyms:3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester	HPLC	≥99.0%	off white
		Single impurity	≤0.3%
		Loss on drying	≤0.5%
		Residue on ignition	≤0.5%
		Assay	≥99.0%
872728-85-3	N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]arbonyl]-N-2-pyridinyl-beta-alanine ethyl ester 4-methylbenzenesulfonate	HPLC	≥97.0%	off white
211915-06-9	Dabigatran Etexilate	HPLC	≥98.0%	white
		Single impurity	≤0.2%
		Loss on drying	≤1.0%
		Assay	≥98.0%
872728-81-9	Dabigatran etexilate mesylate	HPLC	≥99.0%	light yellow solid
		Single impurity	≤0.5%
		Loss on drying	≤1.0%
		Residue on ignition	≤0.1%
		Heavy melta	≤20 ppm
		Assay	≥98.5%

211915 06 9 Thrombin Inhibitor Dabigatran Eexilate CAS 211915 06 9 Blood Thinners Dabigatran Eexilate CAS NUMBER 211915 06 9

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