Empagliflozin Intermediate 6 CAS NUMBER 915095-94-2

Unit Price: USD 1.0000 / Kilogram
Payment Type: T/T
Incoterm: CIF
Min. Order: 1 Kilogram
Delivery Time: 15 Days

Basic Info

Model No.: 915095-94-2

Function: Nervous System Drugs

Additional Info

Packaging: AS REQUIRED

Productivity: KGS


Transportation: Air

Place of Origin: CHINA


Port: Beijing,Shanghai,Shenzhen

Product Description

Empagliflozin intermediate 6 CAS 915095-94-2, Chemical name:(3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furanhe which is the essential intermediate of empagliflozin. According to our understanding, there are many professional registration companies often use 5-bromo-2-chlorobenzoic acid and anisole as raw materials, to get (5-bromo-2-chlorophenyl) (4-methoxyphenyl) methanone, it is important to note that the total yield of this step only 64%. Then Et3SiH, BF3, DCM and the like to get 4-bromo-1-chloro-2- (4-methoxybenzyl) benzene, and the total yield of the reaction was about 60% , Through view those two steps yields situation, basically this route is not feasibility. While Registration companies often do not consider the overall cost of the product to get the final compound as the most important goal, which is fundamentally determines the synthetic method is not suitable for industrial production.

Thera. Category:Anti-diabetes

Cas No.: 915095-94-2

Synonyms:(3S)-3-{4-[(2-chloro-5-iodophenyl)methyl]phenoxy}oxolane;(3S)-3-[4-(2-chloro-5-iodobenzyl)-phenoxy]-tetrahydrofuran;Furan, 3-[4-[(2-chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-, (3S)-;(3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan;(S)-3-(4-(2-chloro-5-iodobenzyl)phenoxy)-tetrahydrofuran;(S)-3-(4-(2-chloro-5-fluorobenzyl)phenoxy)-tetrahydrofuran;EMpagliflozin iMpurity C;(S)-4-iodo-1-chloro-2-(4-tetrahydrofuran-3-yloxy-benzyl)-benzene;


Molecular Formula:C17H16ClFO2

Molecular Weight: 306.7591432

Purity: ≥98%

Packing: Export worthy packing

Material Safety Data Sheet: Available on request

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