|Unit Price:||USD 1.0000 / Kilogram |
|Min. Order:||1 Kilogram|
|Delivery Time:||15 Days|
Model No.: 98475-07-1
Packaging: As required
Place of Origin: CHINA
Certificate: Technical Support
Lenalidomide bromide CAS 98475-07-1. There have been a lot of reports on his preparation methods, the most typical of which are two methods as following:
The first one, 2-methyl-3-nitro-benzoic acid as a raw material, through methyl esterification and bromination reaction to obtain 2-bromomethyl 3-nitro-benzoic acid methyl ester, the method reported time is early, in which the methyl 2-bromomethyl 3-nitro-benzoate was subjected to radical reaction with NBS by ultraviolet light irradiation, and the solvent was refluxed for a long time with carbon tetrachloride or chloroform as a solvent. Obtained by bromination. The reaction conditions are harsh, it is difficult to produce amplification, and a large amount of toxic solvent is used, which is difficult for the labor protection of production workers, and has been rarely used.
The second one, uses 2-methyl-3-nitro-benzoic acid methyl ester as raw material, N-bromosuccinimide (NBS) as brominating reagent, and azobisisobutyronitrile (AIBN) as the initiator, which is harsh in conditions, it is not conducive to industrial production and environmental protection.
Thera. Category: Anti-tumor
Synonyms: 2-BroMoMethyl-3-nitrobenzoate Methyl ester;2-Bromomethyl-3-NitrobenzoicAcidMethylEster;Benzoic acid, 2-(broMoMethyl)-3-nitro-, Methyl ester;Methyl 2-bromomethyl;Lenalidomide Impurity 5;2-Bromomethyl-3-nitro-benzoic acid;Methyl 2-bromomethyl-3-nitrobenzoate;Methyl 2- bromomethyl-3-nitrobezoate;
Packing:Export worthy packing
Material Safety Data Sheet:Available on request