|Unit Price:||USD 100.0000 - 148.0000 / Kilogram |
|Min. Order:||1 Kilogram|
|Delivery Time:||5 Days|
Model No.: 534-07-6
Place of Origin: CHINA
Supply Ability: UNLIMITED
1,3-Dichloroacetone CAS number is 534-07-6, an important pharmaceutical and pesticide intermediate. It is currently used for the synthesis of ciprofloxacin, a quinolone antibacterial agent. There is a literature in the United States that describes his synthesis method. Chlorine and acetone are used as raw materials for the direct chlorination to prepare 1,3-dichloroacetone. In the course of the reaction, a large amount of 1,1-dichloroacetone and trichloroacetone derivatives are generated at the same time, and it is necessary to perform filtration separation to obtain qualified 1,3-dichloroacetone. In addition, this method requires the use of a amount of catalytic of iodine or iodide salt. Because iodine is very expensive. Therefore, the recycling of iodine or iodized salt has to be considered in this process, but it also increases the complexity of the entire production process. So the cost of this method is very high. Some people have improved this method and only two steps are required to obtain: (1) Chlorination. Chlorine and acetone are chlorinated to give monochloroacetone. (2) Suihua,add a platinum catalyst into the monochloroacetone solution obtained in the step (1),optionally a strong acid, is subjected to oximation to give acetone and 1,3-dichloroacetone. Through extract to get the target product. During the course of the operation you will be surprised to find that the acetone and 1,3-dichloroacetone are simultaneously produced when the monochloroacetone and the platinum catalyst are heated, without any significant amount of 1,1-dichloroacetone or high chlorinated by products. .
The platinum catalyst is present in homogeneous form regardless of whether it is added as an insoluble salt.
Thera. Category: Organic Raw material
Synonym:2-Propanone,1,3-dichloro- ;SYM-DICHLOROACETONE;,-Dichloroacetone ;1,3-dichloro-2-propanon ;1,3-dichloroacetona ;1,3-dichloro-propan-2-one ;1,3-dichloropropanone ;2-Propanone, 1,3-dichloro-;
Molecular Weight: 126.97
Specifications: Available on request
Packing: Export worthy packing
Material Safety Data Sheet: Available on request