|Min. Order:||1 Gram|
Model No.: 1405-20-5
Place of Origin: CHINA
Supply Ability: COMMERCIAL
Polymyxin B sulfate CAS number 1405-20-5 is a kind of basic peptide antibiotic which is produced by polymyxes and composed of many kinds of amino acids and fatty acids. It is a multi-component product, including polymyxin B1, B2, B3, B1-1, where B1 and B2 are the active ingredients, B3 and B1-1 are the main impurities.Polymyxin B sulfate CAS 1405-20-5 almost have antibacterial effect on the Gram-negative bacteria, due to the high efficient on Pseudomonas aeruginosa, was the first choice for anti-Pseudomonas aeruginosa drugs, now is currently effective for the treatment of super bacteria, so it paid by much attention, but its impurities B3 and B1-1 have big toxic side effects, a serious impact on the clinical use of polymyxin B. At present, the main use is for external, but only for the local use of sensitive bacteria in the eyes, ears, skin, mucosal infection and burn infection of Pseudomonas aeruginosa. At present, the production of polymyxin B sulfate CAS number 1405-20-5 is mainly biosynthesis by microbial fermentation, and then refined and purified, the impurity B3 is about 3.5% and the impurity B1-1 is 7.5%. if further achieve to oral or injectable drug requirements, it must be innovative technology to further reduce the B3 and B1-1 these two impurities.
Thera. Category: Anti-Biotics
Cas No.: 1405-20-5
Synonym:POLYMYXIN B SULFATE;POLYMYXIN B SULFATE, BACILLUS POLYMYXA;POLYMYXIN B SULFATE SALT;POLYMYXIN B SULPHATE;POLYMYXIN B (PMB);POLYMIXIN B SULFATE;POLYMYXIN B;POLYMYXIN-B 2,5-SULFATE;
Molecular Formula: C56H100N16O17S
Molecular Weight: 1301.56
Pharmacopeia: in house spe.
Specifications:Available on request
Packing:Export worthy packing
Material Safety Data Sheet:Available on request