Pulmonary Hypertension Treatment Ambrisentan 177036-94-1

Unit Price: USD 1.0000 / Kilogram
Payment Type: L/C,T/T
Min. Order: 1 Kilogram
Delivery Time: 15 Days

Basic Info

Model No.: 177036-94-1

Additional Info

Packaging: AS REQUIRED

Productivity: 10KGS/M


Transportation: Air

Place of Origin: CHINA

Supply Ability: UNLIMITED

Certificate: ISO

Product Description

Ambrisentan cas number 177036-94-1 is an endothelin receptor antagonist, clinically suitable for the treatment of pulmonary hypertension. There are currently three types of endothelin receptor antagonists listed: bosentan, Sitaxentan sodium and Ambrisentan . The effect of bosentan and Sitaxentan sodium was not satisfactory, and patients taking Sitaxentan or bosentan had a higher incidence of abnormal liver function, resulting in elevated blood transaminase levels. This adverse reaction can generally reduce the dose or temporary withdrawal control, but the patient must be regular monitoring, if necessary, to be permanently discontinued. The combination of sitaxentan and warfarin in the treatment of pulmonary hypertension has interaction effect. While Ambrisentan is not the interaction with warfarin when combined together., so Ambrisentan cas number 177036-94-1 has obvious advantages in pulmonary hypertension treatment. Ambrisentan cas number 177036-94-1 by oral administration, can quickly absorb into the body cycle, with a high bioavailability, food does not affect its bioavailability. Give only one a day. Clinical trials show that Ambrisentan has good safety and tolerance. In the phase II clinical trial, the adverse effects of patients taking Ambrisentan 177036-94-1were mildly swollen, upper respiratory tract infection, epistaxis, headache, nausea, vomiting, and no dose-dependent. In the long-term use of Ambrisentan patients, taking Ambrisentan till one year, no emergency safety incidents.

Thera. Category:Pulmonary Hypertension Treatment
Cas No.:177036-94-1
Synonym: BSF 208075, AMBRISENTAN;2-(4,6-Dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-di(phenyl)propanoic acid;(aS)-a-[(4,6-Dimethyl-2-pyrimidinyl)oxy]--methoxy--phenylbenzenepropanoic Acid;BSF 208075;LU 208075,bsf-208075

Molecular Formula:C22H22N2O4
Molecular Weight:378.42
Pharmacopeia: in house spe.
Specifications:Available on request
Packing:Export worthy packing
Material Safety Data Sheet:Available on request

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