Small Molecule Inhibitor Alagebrium Chloride 341028-37-3

Payment Type: T/T
Incoterm: CIF
Min. Order: 1 Gram
Delivery Time: 20 Days

Basic Info

Model No.: 341028-37-3

Additional Info

Packaging: AS REQUIRED

Productivity: G,KGS,


Transportation: Air

Place of Origin: CHINA


Certificate: GMP/ISO

Product Description

Alagebrium Chloride as known as ALT-711 341028-37-3 also called thiazolium chloride, is a kind of small molecule inhibitor, ALT711 341028-37-3 was the first drug candidate to be clinically tested for the purpose of breaking the crosslinks caused by advanced glycation endproducts (AGEs), thereby reversing one of the main mechanisms of aging [1]. Through this effect Alagebrium is designed to reverse the stiffening of blood vessel walls that contributes to hypertension and cardiovascular disease, as well as many other forms of degradation associated with protein crosslinking. Alagebrium has proven effective in reducing systolic blood pressure and providing therapeutic benefit for patients with diastolic heart failure. In vitro, the chelating activity of ALT711 on copper-catalyzed oxidation of AA is considerable, and IC50 is 1.92 ± 0.20 mM

  • Thera. Category: Antiatherosclerotic
  • Cas No.: 341028-37-3
  • Synonym: ALT 711; ALT-711; ALT711; 2-(4,5-dimethyl-1,3-thiazol-3-yl)-1-phenyl-ethanone chloride; 4,5-dimethyl-3-(2-oxo-2-phenylethyl)thiazolium chloride;alagebrium chloride; ALT-711; Dimethyl-3-(2-oxo-2-phenyl)-chloride; (Alagebrium) (thiazolium salt); 4,5-Dimethyl-3-(2-oxo-2-phenyl)-thiazoliumchloride;2-(4,5-dimethyl-1,3-thiazol-3-ium-3-yl)-1-phenylethanone chloride
  • Molecular Formula: C13H14ClNOS
  • ALT711 341028-37-3
  • Molecular Weight: 267.77
  • Specifications: Available on request
  • Packing: Export worthy packing
  • Material Safety Data Sheet: Available on request
    Usage: In treatment of cardiovascular complications of diabetes and aging.

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